Down-regulation of lipocalin 2 contributes to chemoresistance in glioblastoma cells
نویسندگان
چکیده
منابع مشابه
Down-Regulation of Lipocalin 2 Expression in Mouse Testis after Exposure to Electromagnetic Field
Background: The effects of electromagnetic field (EMF) on reproductive system have been of critical concern for a long time. It has been shown that the EMF can adversely affect testicular cells and tissue and decrease male fertility. The most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...
متن کاملdown-regulation of lipocalin 2 expression in mouse testis after exposure to electromagnetic field
background: the effects of electromagnetic field (emf) on reproductive system have been of critical concern for a long time. it has been shown that the emf can adversely affect testicular cells and tissue and decrease male fertility. the most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...
متن کاملDown-Regulation of CD14 Transcripts in Human Glioblastoma Cell Line U87 MG
Background: Pattern recognition receptors (PRRs) are the main sensors of pathogen and danger signals in innate immunity of which Toll Like Receptors (TLRs) are the most studied ones. The contribution of PRRs in cerebral inflammation induced by microbial infection, tissue damage and cancer has not extensively been addressed so far. Glioma is the most common tumor of the central nervous system an...
متن کاملDown-Regulation of Metallothionein 1 and 2 after Exposure to Electromagnetic Field in Mouse Testis
Background: It is proved that testis is sensitive to electromagnetic field (EMF) and its damage results in infertility. Exposure to EMF induces reactive oxygen species production and affects on anti-oxidants defense mechanisms. Metallothionein (MT) is a name for a group of low molecular weight (6-7 kDa), sulfhydryl rich proteins. Expression of MT1 and MT2 genes in testis tissue after EMF exposu...
متن کاملRad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation.
We investigated whether Rad51 overexpression plays a role in soft tissue sarcoma (STS) chemoresistance as well as the regulatory mechanisms underlying its expression. The studies reported here show that Rad51 protein is overexpressed in a large panel of human STS specimens. Human STS cell lines showed increased Rad51 protein expression, as was also observed in nude rat STS xenografts. STS cells...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 2009
ISSN: 0022-3042,1471-4159
DOI: 10.1111/j.1471-4159.2009.06410.x